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Last updated: 2016/11/27
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TIRAP MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00114609-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human TIRAP protein.
  • Immunogen:
  • TIRAP (AAH32474.1, 1 a.a. ~ 256 a.a) full-length human protein.
  • Sequence:
  • MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLSGLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRYLQTLSWHLLYHGTPEIGVKLETENPCRASDSHKCDKRYRE
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of TIRAP expression in transfected 293T cell line (H00114609-T01) by TIRAP MaxPab polyclonal antibody.

    Lane 1: TIRAP transfected lysate(28.27 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of TIRAP transfected lysate using anti-TIRAP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TIRAP MaxPab mouse polyclonal antibody (B01) (H00114609-B01).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • TIRAP
  • Gene Alias:
  • FLJ42305,Mal,wyatt
  • Gene Description:
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein
  • Gene Summary:
  • The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
  • Other Designations:
  • MyD88 adapter-like protein,OTTHUMP00000179130,OTTHUMP00000179132,TIR domain-containing adapter protein,TIR domain-containing adaptor protein,Toll-interleukin 1 receptor (TIR) domain-containing adapter protein,Toll-interleukin 1 receptor (TIR) domain-conta
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