GTF3C6 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human GTF3C6 full-length ORF ( NP_612417.1, 1 a.a. - 213 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAAADERSPEDGEDEEEEEQLVLVELSGIIDSDFLSKCENKCKVLGIDTERPILQVDSCVFAGEYEDTLGTCVIFEENVEHADTEGNNKTVLKYKCHTMKKLSMTRTLLTEKKEGEENIGGVEWLQIKDNDFSYRPNMICNFLHENEDEEVVASAPDKSLELEEEEIQMNDSSNLSCEQEKPMHLEIEDSGPLIDIPSETEGSVFMETQMLP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
50.4
Interspecies Antigen Sequence
Mouse (73); Rat (71)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GTF3C6
Entrez GeneID
112495GeneBank Accession#
NM_138408.2Protein Accession#
NP_612417.1Gene Name
GTF3C6
Gene Alias
C6orf51, TFIIIC35, bA397G5.3
Gene Description
general transcription factor IIIC, polypeptide 6, alpha 35kDa
Gene Ontology
HyperlinkGene Summary
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM
Other Designations
OTTHUMP00000017016|transcription factor IIIC 35kDa
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