PRKCDBP polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PRKCDBP.
Immunogen
PRKCDBP (NP_659477, 161 a.a. ~ 261 a.a) partial recombinant protein with GST tag.
Sequence
EVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMESVA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (65); Rat (70)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.22 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PRKCDBP
Entrez GeneID
112464GeneBank Accession#
NM_145040Protein Accession#
NP_659477Gene Name
PRKCDBP
Gene Alias
HSRBC, MGC20400, SRBC
Gene Description
protein kinase C, delta binding protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq
Other Designations
sdr-related gene product that binds to c-kinase
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Interactome
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Disease
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Publication Reference
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Down-regulation of the cavin family proteins in breast cancer.
Bai L, Deng X, Li Q, An W, A D, Gao Z, Xie Y, Dai Y, Cong YS.
Journal of Cellular Biochemistry 2012 Jan; 113(1):322.
Application:IHC-P, WB-Ti, Human, Human breast cancer, MCF-7, MCF10A, MDA-MB-231 cells.
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Down-regulation of the cavin family proteins in breast cancer.
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