BIRC8 MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human BIRC8 protein.
Immunogen
BIRC8 (AAH39318, 1 a.a. ~ 236 a.a) full-length human protein.
Sequence
MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLGVLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSMVIDFKQRVFMS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BIRC8 expression in transfected 293T cell line (H00112401-T01) by BIRC8 MaxPab polyclonal antibody.
Lane 1: BIRC8 transfected lysate(25.96 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — BIRC8
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Interactome
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Publication Reference
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USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.
Engel K,Rudelius M,Slawska J,Jacobs L,Ahangarian Abhari B,Altmann B,Kurutz J,Rathakrishnan A,Fernandez-Saiz V,Brunner A,Targosz BS,Loewecke F,Gloeckner CJ,Ueffing M, Fulda S,Pfreundschuh M,Trumper L,Klapper W,Keller U, Jost PJ,Rosenwald A,Peschel C,Bassermann F.
EMBO Molecular Medicine 2016 Aug; 8(8):851.
Application:WB-Tr, Human, HeLa cells.
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Fisetin induces apoptosis in Huh-7 cells via downregulation of BIRC8 and Bcl2L2.
Kim JY, Jeon YK, Jeon W, Nam MJ.
Food and Chemical Toxicology 2010 Aug; 48(8-9):2259.
Application:WB-Ce, Human, Huh-7 cells.
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USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.
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