MRLC2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human MRLC2 partial ORF ( NP_291024.1, 73 a.a. - 172 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MRLC2
Entrez GeneID
103910GeneBank Accession#
NM_033546Protein Accession#
NP_291024.1Gene Name
MRLC2
Gene Alias
MLC-B
Gene Description
myosin regulatory light chain MRLC2
Omim ID
609211Gene Ontology
HyperlinkGene Summary
The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM
Other Designations
OTTHUMP00000165806|OTTHUMP00000165807|OTTHUMP00000165808|myosin regulatory light chain MRCL2
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