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PPP1R14A rabbit monoclonal antibody

  • Catalog # : H00094274-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PPP1R14A peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PPP1R14A is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PPP1R14A peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Gene Name:
  • PPP1R14A
  • Gene Alias:
  • CPI-17,CPI17,PPP1INL
  • Gene Description:
  • protein phosphatase 1, regulatory (inhibitor) subunit 14A
  • Gene Summary:
  • PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration.[supplied by OMIM
  • Other Designations:
  • 17-KDa protein,17-kDa PKC-potentiated inhibitory protein of PP1,PKC-potentiated inhibitory protein of PP1
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