FOXQ1 monoclonal antibody (M05), clone 2F2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FOXQ1.
Immunogen
FOXQ1 (NP_150285, 110 a.a. ~ 219 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (76)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FOXQ1 is approximately 0.3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to FOXQ1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — FOXQ1
Entrez GeneID
94234GeneBank Accession#
NM_033260Protein Accession#
NP_150285Gene Name
FOXQ1
Gene Alias
HFH1
Gene Description
forkhead box Q1
Gene Ontology
HyperlinkGene Summary
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM
Other Designations
winged helix/forkhead transcription factor
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Interactome
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Publication Reference
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Foxq1 promotes metastasis of nasopharyngeal carcinoma by inducing vasculogenic mimicry via the EGFR signaling pathway.
Yunfan Luo, Jie Wang, Fan Wang, Xiong Liu, Juan Lu, Xiaoxiao Yu, Xuemin Ma, Xiaohong Peng, Xiangping Li.
Cell Death & Disease 2021 Apr; 12(5):411.
Application:IF, Human, 5–8F cells.
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Foxq1 promotes metastasis of nasopharyngeal carcinoma by inducing vasculogenic mimicry via the EGFR signaling pathway.
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