FOXP2 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human FOXP2 full-length ORF ( AAH18016.1, 1 a.a. - 67 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQEDVVSYTQVIC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.6
Interspecies Antigen Sequence
Rat (61)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FOXP2
Entrez GeneID
93986GeneBank Accession#
BC018016.1Protein Accession#
AAH18016.1Gene Name
FOXP2
Gene Alias
CAGH44, DKFZp686H1726, SPCH1, TNRC10
Gene Description
forkhead box P2
Gene Ontology
HyperlinkGene Summary
This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Multiple alternative transcripts encoding different isoforms have been identified. [provided by RefSeq
Other Designations
CAG repeat protein 44|OTTHUMP00000067772|forkhead/winged-helix transcription factor|speech and language disorder 1|trinucleotide repeat containing 10
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Interactomes
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Diseases
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