CAPZA3 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CAPZA3 protein.
Immunogen
CAPZA3 (AAH16745.1, 1 a.a. ~ 299 a.a) full-length human protein.
Sequence
MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDGNPVLLSHHNVMGDYRFFDHQSKLSFKYYLLQNQLKDIQSHGIIQNEAEYLRVVLLCALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRKILRRDLPVTRTLIDWHRILSDLNLVMYPKLGYVIYSRSVLCNWII
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CAPZA3 expression in transfected 293T cell line (H00093661-T01) by CAPZA3 MaxPab polyclonal antibody.
Lane 1: CAPZA3 transfected lysate(35.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CAPZA3 transfected lysate using anti-CAPZA3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CAPZA3 purified MaxPab mouse polyclonal antibody (B01P) (H00093661-B01P). -
Gene Info — CAPZA3
Entrez GeneID
93661GeneBank Accession#
BC016745.2Protein Accession#
AAH16745.1Gene Name
CAPZA3
Gene Alias
CAPPA3, Gsg3
Gene Description
capping protein (actin filament) muscle Z-line, alpha 3
Omim ID
608722Gene Ontology
HyperlinkGene Summary
This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility. [provided by RefSeq
Other Designations
CapZ alpha-3|F-actin capping protein alpha-3 subunit|capping protein alpha 3
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Disease
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Publication Reference
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The expression of human testis-specific actin capping protein predicts in vitro fertilization outcomes: A novel biomarker of sperm function for assisted reproductive technology.
Yusuke Inagaki, Shinichiro Fukuhara, Sohei Kuribayashi, Koichi Okada, Yosuke Sekii, Kentaro Takezawa, Hiroshi Kiuchi, Tetsuji Soda, Yasushi Miyagawa, Yoshio Okamoto, Hiromitsu Tanaka, Norio Nonomura.
Reproductive Medicine and Biology 2021 Aug; 20(4):537.
Application:IHC, Human, Human sperm samples.
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Systematic characterization of human testis-specific actin capping protein β3 as a possible biomarker for male infertility.
Soda T, Miyagawa Y, Ueda N, Takezawa K, Okuda H, Fukuhara S, Fujita K, Kiuchi H, Uemura M, Okamoto Y, Tsujimura A, Tanaka H, Nonomura N.
Human Reproduction 2017 Mar; 32(3):514.
Application:IF, IHC, WB, Human, Human sperm.
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The expression of human testis-specific actin capping protein predicts in vitro fertilization outcomes: A novel biomarker of sperm function for assisted reproductive technology.
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