Products

Western Blot

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

FBXO44

Gene Alias

DKFZp781J0852, FBG3, FBX30, FBX6A, Fbx44, Fbxo6a, MGC14140

Gene Description

F-box protein 44

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq

Other Designations

F-box gene 3|F-box protein FBX30|OTTHUMP00000002063|OTTHUMP00000002064|OTTHUMP00000002065|OTTHUMP00000035896|OTTHUMP00000044368