CHMP4C 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
CHMP4C transfected lysate.
Western Blot
Lane 1: CHMP4C transfected lysate ( 26.4 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CHMP4C full-length
Host
Human
Theoretical MW (kDa)
26.4
Interspecies Antigen Sequence
Mouse (84); Rat (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CHMP4C antibody (H00092421-B01) by Western Blots.
SDS-PAGE Gel
CHMP4C transfected lysate.
Western Blot
Lane 1: CHMP4C transfected lysate ( 26.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CHMP4C
Entrez GeneID
92421GeneBank Accession#
NM_152284Protein Accession#
NP_689497Gene Name
CHMP4C
Gene Alias
MGC22825, SNF7-3, Shax3
Gene Description
chromatin modifying protein 4C
Omim ID
610899Gene Ontology
HyperlinkGene Summary
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM
Other Designations
Snf7 homologue associated with Alix 3
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Interactome
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Pathway
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