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STRADA (Human) IP-WB Antibody Pair

  • Catalog # : H00092335-PW2
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00092335-PW2
    Immunoprecipitation of STRADA transfected lysate using rabbit polyclonal anti-STRADA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-STRADA.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-STRADA (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-STRADA (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Gene Name:
  • Gene Alias:
  • FLJ90524,LYK5,NY-BR-96,PMSE,STRAD,Stlk
  • Gene Description:
  • STE20-related kinase adaptor alpha
  • Gene Summary:
  • The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • STE20-like pseudokinase,STE20-related adaptor protein,protein kinase LYK5
  • Gene Pathway
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