STRADA (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of STRADA transfected lysate using rabbit polyclonal anti-STRADA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-STRADA.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (92)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of STRADA transfected lysate using rabbit polyclonal anti-STRADA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-STRADA.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-STRADA (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-STRADA (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — STRADA
Entrez GeneID
92335Gene Name
STRADA
Gene Alias
FLJ90524, LYK5, NY-BR-96, PMSE, STRAD, Stlk
Gene Description
STE20-related kinase adaptor alpha
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq
Other Designations
STE20-like pseudokinase|STE20-related adaptor protein|protein kinase LYK5
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Interactome
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Pathway
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