STRADA MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
STRADA MaxPab rabbit polyclonal antibody. Western Blot analysis of STRADA expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of STRADA expression in transfected 293T cell line (H00092335-T01) by STRADA MaxPab polyclonal antibody.
Lane 1: STRADA transfected lysate(38.6 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of STRADA transfected lysate using anti-STRADA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with STRADA purified MaxPab mouse polyclonal antibody (B01P) (H00092335-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human STRADA protein.
Immunogen
STRADA (NP_699166.2, 1 a.a. ~ 348 a.a) full-length human protein.
Sequence
MSFLTNDASSESIASFSKQEVMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDFPKYSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVPFKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSVANSGLSDSLTTSTPRPSNGDSPSHPYHRTFSPHFHHFVEQCLQRNPDARYPCWPGPGLRESRGCSGG
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
STRADA MaxPab rabbit polyclonal antibody. Western Blot analysis of STRADA expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of STRADA expression in transfected 293T cell line (H00092335-T01) by STRADA MaxPab polyclonal antibody.
Lane 1: STRADA transfected lysate(38.6 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of STRADA transfected lysate using anti-STRADA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with STRADA purified MaxPab mouse polyclonal antibody (B01P) (H00092335-B01P). -
Gene Info — STRADA
Entrez GeneID
92335GeneBank Accession#
NM_153335Protein Accession#
NP_699166.2Gene Name
STRADA
Gene Alias
FLJ90524, LYK5, NY-BR-96, PMSE, STRAD, Stlk
Gene Description
STE20-related kinase adaptor alpha
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq
Other Designations
STE20-like pseudokinase|STE20-related adaptor protein|protein kinase LYK5
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Interactome
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Pathway
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