NLRP12 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NLRP12 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NLRP12 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NLRP12 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NLRP12
Entrez GeneID
91662GeneBank Accession#
NLRP12Gene Name
NLRP12
Gene Alias
CLR19.3, FCAS2, NALP12, PAN6, PYPAF7, RNO, RNO2
Gene Description
NLR family, pyrin domain containing 12
Omim ID
609648Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined. [provided by RefSeq
Other Designations
NACHT, LRR and PYD containing protein 12|NACHT, leucine rich repeat and PYD containing 12|OTTHUMP00000067226|PYRIN-containing APAF1-like protein 7|monarch 1|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12|regu
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Interactome
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Disease
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