UBXN11 monoclonal antibody (M01), clone 1B10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant UBXN11.
Immunogen
UBXN11 (NP_663320.1, 311 a.a. ~ 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.41 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UBXN11 is 0.1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to UBXN11 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — UBXN11
Entrez GeneID
91544GeneBank Accession#
NM_145345Protein Accession#
NP_663320.1Gene Name
UBXN11
Gene Alias
COA-1, DKFZp686F04228, PP2243, SOC, SOCI, UBXD5
Gene Description
UBX domain protein 11
Omim ID
609151Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000003460|OTTHUMP00000003461|OTTHUMP00000003462|OTTHUMP00000003463|UBX domain containing 5|colorectal tumor-associated antigen-1|socius
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