LRSAM1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LRSAM1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human LRSAM1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LRSAM1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LRSAM1
Entrez GeneID
90678GeneBank Accession#
LRSAM1Gene Name
LRSAM1
Gene Alias
FLJ31641, RIFLE, TAL
Gene Description
leucine rich repeat and sterile alpha motif containing 1
Omim ID
610933Gene Ontology
HyperlinkGene Summary
LRSAM1 is a multifunctional RING finger protein that selectively regulates cell adhesion molecules, has ubiquitin ligase activity, and plays a role in receptor endocytosis and viral budding (Li et al., 2003 [PubMed 14635195]; Amit et al., 2004 [PubMed 15256501]).[supplied by OMIM
Other Designations
OTTHUMP00000022174|OTTHUMP00000022175|Tsg101-associated ligase
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Interactome
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