MCU rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MCU peptide using ARM Technology.
Immunogen
A synthetic peptide of human MCU is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MCU peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MCU
Entrez GeneID
90550GeneBank Accession#
MCUGene Name
MCU
Gene Alias
C10orf42, CCDC109A
Gene Description
mitochondrial calcium uniporter
Gene Ontology
HyperlinkGene Summary
mitochondrial; coiled-coil domain-containing protein 109A
Other Designations
calcium uniporter protein, mitochondrial; coiled-coil domain-containing protein 109A
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Interactome
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Publication Reference
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Mitochondrial Targeted Peptides Preserve Mitochondrial Organization and Decrease Reversible Myocardial Changes in Early Swine Metabolic Syndrome.
Yuan F, Woollard JR, Jordan KL, Lerman A, Lerman LO, Eirin A.
Cardiovascular Research 2018 Mar; 114(3):431.
Application:WB, Pig, Pig myocardial mitochondria.
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Mitochondrial Targeted Peptides Preserve Mitochondrial Organization and Decrease Reversible Myocardial Changes in Early Swine Metabolic Syndrome.
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