SLC25A21 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SLC25A21 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SLC25A21 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SLC25A21 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SLC25A21
Entrez GeneID
89874GeneBank Accession#
SLC25A21Gene Name
SLC25A21
Gene Alias
MGC126570, ODC, ODC1
Gene Description
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
Omim ID
607571Gene Ontology
HyperlinkGene Summary
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM
Other Designations
oxodicarboxylate carrier
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Interactome
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Disease
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