SSH2 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human SSH2 full-length ORF ( AAH11636.2, 1 a.a. - 178 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MIPYFSANAVISQNAINQLISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWVDRDSRNKHCDVLLVEE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.3
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SSH2
Entrez GeneID
85464GeneBank Accession#
BC011636.2Protein Accession#
AAH11636.2Gene Name
SSH2
Gene Alias
KIAA1725, MGC78588, SSH-2
Gene Description
slingshot homolog 2 (Drosophila)
Omim ID
606779Gene Ontology
HyperlinkGene Summary
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM
Other Designations
slingshot 2
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Interactome
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Pathway
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Disease
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