SSH2 monoclonal antibody (M07), clone 1E11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SSH2.
Immunogen
SSH2 (NP_203747, 20 a.a. ~ 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ASEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SSH2 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — SSH2
Entrez GeneID
85464GeneBank Accession#
NM_033389Protein Accession#
NP_203747Gene Name
SSH2
Gene Alias
KIAA1725, MGC78588, SSH-2
Gene Description
slingshot homolog 2 (Drosophila)
Omim ID
606779Gene Ontology
HyperlinkGene Summary
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM
Other Designations
slingshot 2
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Interactome
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Pathway
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Disease
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