SSH2 MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SSH2 protein.
Immunogen
SSH2 (AAH11636.2, 1 a.a. ~ 178 a.a) full-length human protein.
Sequence
MIPYFSANAVISQNAINQLISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWVDRDSRNKHCDVLLVEE
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SSH2 expression in transfected 293T cell line (H00085464-T02) by SSH2 MaxPab polyclonal antibody.
Lane 1: SSH2 transfected lysate(19.9 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SSH2 transfected lysate using anti-SSH2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SSH2 MaxPab mouse polyclonal antibody (B01) (H00085464-B01). -
Gene Info — SSH2
Entrez GeneID
85464GeneBank Accession#
BC011636.2Protein Accession#
AAH11636.2Gene Name
SSH2
Gene Alias
KIAA1725, MGC78588, SSH-2
Gene Description
slingshot homolog 2 (Drosophila)
Omim ID
606779Gene Ontology
HyperlinkGene Summary
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM
Other Designations
slingshot 2
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Interactome
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Pathway
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Disease
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