ZCRB1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ZCRB1 protein.
Immunogen
ZCRB1 (NP_149105.3, 1 a.a. ~ 217 a.a) full-length human protein.
Sequence
MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGVPSTSDDSRRPRIKKSTYFSDEEELSD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ZCRB1 expression in transfected 293T cell line (H00085437-T01) by ZCRB1 MaxPab polyclonal antibody.
Lane 1: ZCRB1 transfected lysate(23.87 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ZCRB1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ZCRB1
Entrez GeneID
85437GeneBank Accession#
NM_033114.3Protein Accession#
NP_149105.3Gene Name
ZCRB1
Gene Alias
MADP-1, MADP1, MGC26805, RBM36, ZCCHC19
Gene Description
zinc finger CCHC-type and RNA binding motif 1
Omim ID
610750Gene Ontology
HyperlinkGene Summary
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq
Other Designations
U11/U12 snRNP 31K
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