NKD2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human NKD2 full-length ORF ( AAH12176, 1 a.a. - 311 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGKLQSKHAAAARKRRESPEGDSFVASAYASGRKGAEEAERRARDKQELPNGDPKEGPFREDQCPLQVALPAEKAEGREHPGQLLSADDGERAANREGPRGPGGQRLNIDALQCDVSVEEDDRQEWTFTLYDFDNCGKVTREDMSSLMHTIYEVVDASVNHSSGSSKTLRVKLTVSPEPSSKRKEGPPAGQDREPTRCRMEGELAEEPRVADRRLSAHVRRPSTDPQPCSERGPYCVDENTERRNHYLDLAGIENYTSRFGPGSQLCEKRSSAPRTHSGDKARGVGLCRELWSQAGHPQWPGPFPSGLVAV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
59.95
Interspecies Antigen Sequence
Mouse (78); Rat (78)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NKD2
Entrez GeneID
85409GeneBank Accession#
BC012176Protein Accession#
AAH12176Gene Name
NKD2
Gene Alias
Naked2
Gene Description
naked cuticle homolog 2 (Drosophila)
Omim ID
607852Gene Ontology
HyperlinkGene Summary
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM
Other Designations
Dvl-binding protein NKD2|naked cuticle homolog 2|naked cuticle-2
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Pathway
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