TRIM5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TRIM5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TRIM5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TRIM5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TRIM5
Entrez GeneID
85363GeneBank Accession#
TRIM5Gene Name
TRIM5
Gene Alias
RNF88, TRIM5alpha
Gene Description
tripartite motif-containing 5
Omim ID
608487Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Five alternatively spliced transcript variants for this gene have been described. However, the full length nature of two of the variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000069811|OTTHUMP00000069812|tripartite motif protein TRIM|tripartite motif protein TRIM5|tripartite motif-containing protein 5 alpha
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Interactome
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Disease
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