ABCC11 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
ABCC11 transfected lysate.
Western Blot
Lane 1: ABCC11 transfected lysate ( 62.10 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ABCC11 full-length
Host
Human
Theoretical MW (kDa)
62.1
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ABCC11 antibody (H00085320-B01P) by Western Blots.
SDS-PAGE Gel
ABCC11 transfected lysate.
Western Blot
Lane 1: ABCC11 transfected lysate ( 62.10 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ABCC11
Entrez GeneID
85320GeneBank Accession#
BC039085Protein Accession#
AAH39085Gene Name
ABCC11
Gene Alias
EWWD, MRP8, WW
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette protein C11|ATP-binding cassette transporter MRP8|ATP-binding cassette, sub-family C, member 11|OTTHUMP00000164191|multi-resistance protein 8
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Interactome
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Pathway
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Disease
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