ABCC11 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of ABCC11 transfected lysate using rabbit polyclonal anti-ABCC11 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ABCC11.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-ABCC11 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-ABCC11 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — ABCC11
Entrez GeneID
85320Gene Name
ABCC11
Gene Alias
EWWD, MRP8, WW
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette protein C11|ATP-binding cassette transporter MRP8|ATP-binding cassette, sub-family C, member 11|OTTHUMP00000164191|multi-resistance protein 8
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Interactome
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Disease
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