ATG4D rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ATG4D peptide using ARM Technology.
Immunogen
A synthetic peptide of human ATG4D is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ATG4D peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ATG4D
Entrez GeneID
84971GeneBank Accession#
ATG4DGene Name
ATG4D
Gene Alias
APG4-D, APG4D, AUTL4
Gene Description
ATG4 autophagy related 4 homolog D (S. cerevisiae)
Omim ID
611340Gene Ontology
HyperlinkGene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq
Other Designations
APG4 autophagy 4 homolog D|AUT-like 4, cysteine endopeptidase|autophagin-4|autophagy-related cysteine endopeptidase 4|cysteine protease involved in autophagy
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Pathway
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