TNFRSF19L monoclonal antibody (M01), clone 3F8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNFRSF19L.
Immunogen
TNFRSF19L (NP_116260, 26 a.a. ~ 124 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
STTLWQCPPGEEPDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGMATRDTLCGDCWPGWFGPWGVPRVPCQPCSWAPLGTHGCDEW
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TNFRSF19L expression in transfected 293T cell line by TNFRSF19L monoclonal antibody (M01), clone 3F8.
Lane 1: TNFRSF19L transfected lysate(46.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RELT is 0.1 ng/ml as a capture antibody.ELISA
RNAi Knockdown (Antibody validated)
Western blot analysis of TNFRSF19L over-expressed 293 cell line, cotransfected with TNFRSF19L Validated Chimera RNAi ( Cat # H00084957-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with TNFRSF19L monoclonal antibody (M01), clone 3F8 (Cat # H00084957-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. -
Gene Info — RELT
Entrez GeneID
84957GeneBank Accession#
NM_032871Protein Accession#
NP_116260Gene Name
RELT
Gene Alias
FLJ14993, TNFRSF19L
Gene Description
RELT tumor necrosis factor receptor
Omim ID
611211Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq
Other Designations
receptor expressed in lymphoid tissues|tumor necrosis factor receptor superfamily, member 19-like
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Interactome
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Pathway
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