HSH2D rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HSH2D peptide using ARM Technology.
Immunogen
A synthetic peptide of human HSH2D is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HSH2D peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HSH2D
Entrez GeneID
84941GeneBank Accession#
HSH2DGene Name
HSH2D
Gene Alias
ALX, FLJ14886, HSH2
Gene Description
hematopoietic SH2 domain containing
Omim ID
608349Gene Ontology
HyperlinkGene Summary
T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM
Other Designations
adaptor in lymphocytes of unknown function X|hematopoietic SH2 protein
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Interactome
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Disease
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