CIRH1A polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CIRH1A.
Immunogen
CIRH1A (NP_116219, 587 a.a. ~ 686 a.a) partial recombinant protein with GST tag.
Sequence
SFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CIRH1A polyclonal antibody (A01), Lot # 060112JC01. Western Blot analysis of CIRH1A expression in Daoy.Western Blot (Recombinant protein)
ELISA
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Gene Info — CIRH1A
Entrez GeneID
84916GeneBank Accession#
NM_032830Protein Accession#
NP_116219Gene Name
CIRH1A
Gene Alias
CIRHIN, FLJ14728, FLJ17146, KIAA1988, NAIC, TEX292
Gene Description
cirrhosis, autosomal recessive 1A (cirhin)
Gene Ontology
HyperlinkGene Summary
This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. [provided by RefSeq
Other Designations
cirhin|testis expressed gene 292
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Interactome
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Publication Reference
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NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.
Freed EF, Prieto JL, McCann KL, McStay B, Baserga SJ.
PLoS Genetics 2012 Aug; 8(8):e1002892.
Application:WB-Tr, Human, HeLa cells.
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NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.
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