CBR4 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human CBR4 full-length ORF ( AAH21973.1, 1 a.a. - 237 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESPYITGHVLVVDGGLQLIL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
51.7
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CBR4
Entrez GeneID
84869GeneBank Accession#
BC021973.2Protein Accession#
AAH21973.1Gene Name
CBR4
Gene Alias
FLJ14431, SDR45C1
Gene Description
carbonyl reductase 4
Gene Ontology
HyperlinkGene Summary
member 1
Other Designations
carbonic reductase 4|short chain dehydrogenase/reductase family 45C, member 1
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Interactome
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Publication Reference
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Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin.
Sawamura R, Sakurai H, Wada N, Nishiya Y, Honda T, Kazui M, Kurihara A, Shinagawa A, Izumi T.
Biopharmaceutics & Drug Disposition 2015 Sep; 36(6):352.
Application:WB-Re, Human, 293-F cells.
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In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism.
Atsriku C, Hoffmann M, Moghaddam M, Kumar G, Surapaneni S.
Xenobiotica 2015 Jun; 45(6):465.
Application:Enzyme, Human, Tanzisertib were incubated in human liver microsomes, cytosol and hepatocytes.
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Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin.
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