HAVCR2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human HAVCR2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — HAVCR2
Entrez GeneID
84868GeneBank Accession#
BC020843.1Protein Accession#
AAH20843.1Gene Name
HAVCR2
Gene Alias
FLJ14428, KIM-3, TIM3, TIMD3, Tim-3
Gene Description
hepatitis A virus cellular receptor 2
Omim ID
606652Gene Ontology
HyperlinkGene Summary
CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM
Other Designations
T cell immunoglobulin mucin 3|T cell immunoglobulin mucin-3|kidney injury molecule-3
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Interactome
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Disease
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