LNX (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human LNX partial ORF ( NP_116011, 19 a.a. - 118 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DNVGNLHFLYSELCKGAFHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQPAISPVDSGRSNRTRARPFERS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (80); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LNX1
Entrez GeneID
84708GeneBank Accession#
NM_032622Protein Accession#
NP_116011Gene Name
LNX1
Gene Alias
LNX, MPDZ, PDZRN2
Gene Description
ligand of numb-protein X 1
Omim ID
609732Gene Ontology
HyperlinkGene Summary
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000128294|PDZ domain-containing ring finger protein 2|multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX
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Interactome
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Disease
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