FBXL10 (Human) Recombinant Protein (Q01)
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More Files
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Specifications
Product Description
Human FBXL10 partial ORF ( NP_115979, 457 a.a. - 555 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (93); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FBXL10
Entrez GeneID
84678GeneBank Accession#
NM_032590Protein Accession#
NP_115979Gene Name
FBXL10
Gene Alias
CXXC2, Fbl10, JHDM1B, KDM2B, PCCX2
Gene Description
F-box and leucine-rich repeat protein 10
Omim ID
609078Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein|jumonji C domain-containing histone demethylase 1B|protein containing CXXC domain 2
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Interactomes
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Diseases
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