TRIM63 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human TRIM63 full-length ORF ( NP_115977.2, 1 a.a. - 353 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
66.6
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TRIM63
Entrez GeneID
84676GeneBank Accession#
NM_032588.2Protein Accession#
NP_115977.2Gene Name
TRIM63
Gene Alias
FLJ32380, IRF, MURF1, MURF2, RNF28, SMRZ
Gene Description
tripartite motif-containing 63
Omim ID
606131Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq
Other Designations
OTTHUMP00000008701|iris ring finger protein|muscle specific ring finger protein 1|muscle specific ring finger protein 2|ring finger protein 28|striated muscle RING zinc finger protein
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