TRIM63 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TRIM63 protein.
Immunogen
TRIM63 (NP_115977.2, 1 a.a. ~ 353 a.a) full-length human protein.
Sequence
MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TRIM63 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRIM63 expression in mouse testis.Western Blot (Tissue lysate)
TRIM63 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRIM63 expression in human stomach.Western Blot (Cell lysate)
TRIM63 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRIM63 expression in MCF-7.Western Blot (Cell lysate)
TRIM63 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRIM63 expression in NIH/3T3.Western Blot (Transfected lysate)
Western Blot analysis of TRIM63 expression in transfected 293T cell line (H00084676-T02) by TRIM63 MaxPab polyclonal antibody.
Lane 1: TRIM63 transfected lysate(40.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of TRIM63 transfected lysate using anti-TRIM63 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TRIM63 purified MaxPab mouse polyclonal antibody (B01P) (H00084676-B01P). -
Gene Info — TRIM63
Entrez GeneID
84676GeneBank Accession#
NM_032588.2Protein Accession#
NP_115977.2Gene Name
TRIM63
Gene Alias
FLJ32380, IRF, MURF1, MURF2, RNF28, SMRZ
Gene Description
tripartite motif-containing 63
Omim ID
606131Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq
Other Designations
OTTHUMP00000008701|iris ring finger protein|muscle specific ring finger protein 1|muscle specific ring finger protein 2|ring finger protein 28|striated muscle RING zinc finger protein
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Interactome
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Publication Reference
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Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS.
Meinen S, Lin S, Rüegg MA, Punga AR.
PLoS One 2012 Aug; 7(8):e44148.
Application:WB-Ti, Mouse, Mouse muscle.
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Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS.
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