TRIM63 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant TRIM63.
Immunogen
TRIM63 (NP_115977, 254 a.a. ~ 352 a.a) partial recombinant protein with GST tag.
Sequence
DKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TRIM63 polyclonal antibody (A01), Lot # 051219JC01 Western Blot analysis of TRIM63 expression in HepG2 ( Cat # L019V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — TRIM63
Entrez GeneID
84676GeneBank Accession#
NM_032588Protein Accession#
NP_115977Gene Name
TRIM63
Gene Alias
FLJ32380, IRF, MURF1, MURF2, RNF28, SMRZ
Gene Description
tripartite motif-containing 63
Omim ID
606131Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq
Other Designations
OTTHUMP00000008701|iris ring finger protein|muscle specific ring finger protein 1|muscle specific ring finger protein 2|ring finger protein 28|striated muscle RING zinc finger protein
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