TRIM55 monoclonal antibody (M02), clone 1A1
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant TRIM55.
Immunogen
TRIM55 (AAH07750, 1 a.a. ~ 452 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQIGFEAPPLQGQAAAPASGSGADSEPARHIFSFSWLNSLNE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (82)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (75.46 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TRIM55 monoclonal antibody (M02), clone 1A1. Western Blot analysis of TRIM55 expression in human stomach.Western Blot (Cell lysate)
TRIM55 monoclonal antibody (M02), clone 1A1. Western Blot analysis of TRIM55 expression in HeLa(Cat # L013V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TRIM55 is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — TRIM55
Entrez GeneID
84675GeneBank Accession#
BC007750Protein Accession#
AAH07750Gene Name
TRIM55
Gene Alias
MURF-2, RNF29
Gene Description
tripartite motif-containing 55
Omim ID
606469Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
muscle specific ring finger 2|ring finger protein 29
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Interactome
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Disease
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Publication Reference
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TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease.
Zi-Yang Zhang, Dilshan S Harischandra, Ruifang Wang, Shivani Ghaisas, Janet Y Zhao, Thomas P McMonagle, Guixin Zhu, Kenzo D Lacuarta, Jianing Song, John Q Trojanowski, Hong Xu, Virginia M-Y Lee, Xiaolu Yang
Science 2023 Jul; 381(6656):eadd6696.
Application:WB, Human, HEK293T, Human brain, N2a cells.
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TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease.
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