HES7 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human HES7 full-length ORF ( NP_115969.2, 1 a.a. - 225 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
51.15
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HES7
Entrez GeneID
84667GeneBank Accession#
NM_032580.2Protein Accession#
NP_115969.2Gene Name
HES7
Gene Alias
bHLHb37
Gene Description
hairy and enhancer of split 7 (Drosophila)
Omim ID
608059Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
bHLH factor Hes7|hairy and enhancer of split 7
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Interactome
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Disease
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