PARD6B (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PARD6B full-length ORF ( AAH60847, 1 a.a. - 372 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
66.66
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PARD6B
Entrez GeneID
84612GeneBank Accession#
BC060847Protein Accession#
AAH60847Gene Name
PARD6B
Gene Alias
PAR6B
Gene Description
par-6 partitioning defective 6 homolog beta (C. elegans)
Omim ID
608975Gene Ontology
HyperlinkGene Summary
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq
Other Designations
OTTHUMP00000031269|PAR-6 beta
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Interactome
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Pathway
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Publication Reference
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Ceramide regulates atypical PKCzeta /lambda -mediated cell polarity in primitive ectoderm cells: A novel function of sphingolipids in morphogenesis.
Krishnamurthy K, Wang G, Silva J, Condie BG, Bieberich E.
The Journal of Biological Chemistry 2006 Nov; 282(5):3379.
Application：WB, PS/Cer vesicles.
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Ceramide regulates atypical PKCzeta /lambda -mediated cell polarity in primitive ectoderm cells: A novel function of sphingolipids in morphogenesis.
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