COL25A1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-COL25A1 full-length
Host
Human
Theoretical MW (kDa)
54.67
Interspecies Antigen Sequence
Mouse (75)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-COL25A1 antibody (H00084570-B01) by Western Blots.
SDS-PAGE Gel
COL25A1 transfected lysate.
Western Blot
Lane 1: COL25A1 transfected lysate ( 54.67 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — COL25A1
Entrez GeneID
84570GeneBank Accession#
BC036669.2Protein Accession#
AAH36669.1Gene Name
COL25A1
Gene Alias
CLAC, CLACP
Gene Description
collagen, type XXV, alpha 1
Omim ID
610004Gene Ontology
HyperlinkGene Summary
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]).[supplied by OMIM
Other Designations
OTTHUMP00000196081|OTTHUMP00000196082|collagen-like Alzheimer amyloid plaque component|collagenous Alzheimer amyloid plaque component
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Interactome
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Disease
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