COL25A1 monoclonal antibody (M01), clone 1D2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant COL25A1.
Immunogen
COL25A1 (NP_942014.1, 57 a.a. ~ 122 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NDLQARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged COL25A1 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — COL25A1
Entrez GeneID
84570GeneBank Accession#
NM_198721Protein Accession#
NP_942014.1Gene Name
COL25A1
Gene Alias
CLAC, CLACP
Gene Description
collagen, type XXV, alpha 1
Omim ID
610004Gene Ontology
HyperlinkGene Summary
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]).[supplied by OMIM
Other Designations
OTTHUMP00000196081|OTTHUMP00000196082|collagen-like Alzheimer amyloid plaque component|collagenous Alzheimer amyloid plaque component
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Interactome
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Disease
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