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Last updated: 2017/11/19

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COL25A1 rabbit monoclonal antibody

  • Catalog # : H00084570-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human COL25A1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human COL25A1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human COL25A1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • COL25A1
  • Gene Alias:
  • CLAC,CLACP
  • Gene Description:
  • collagen, type XXV, alpha 1
  • Gene Summary:
  • COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000196081,OTTHUMP00000196082,collagen-like Alzheimer amyloid plaque component,collagenous Alzheimer amyloid plaque component
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