COL25A1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human COL25A1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human COL25A1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human COL25A1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — COL25A1
Entrez GeneID
84570GeneBank Accession#
COL25A1Gene Name
COL25A1
Gene Alias
CLAC, CLACP
Gene Description
collagen, type XXV, alpha 1
Omim ID
610004Gene Ontology
HyperlinkGene Summary
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]).[supplied by OMIM
Other Designations
OTTHUMP00000196081|OTTHUMP00000196082|collagen-like Alzheimer amyloid plaque component|collagenous Alzheimer amyloid plaque component
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Interactome
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Disease
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