HOPX rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HOPX peptide using ARM Technology.
Immunogen
A synthetic peptide of human HOPX is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HOPX peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HOPX
Entrez GeneID
84525GeneBank Accession#
HOPXGene Name
HOPX
Gene Alias
Cameo, HOP, LAGY, MGC20820, NECC1, OB1, SMAP31, Toto
Gene Description
HOP homeobox
Omim ID
607275Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000158970|heart odd homeobox 1 protein|homeodomain-only protein|lung cancer-associated Y protein|not expressed in choriocarcinoma clone 1
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Interactome
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