LCOR (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human LCOR full-length ORF ( AAH53359.1, 1 a.a. - 406 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATTQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCAGSTSLSHSPGCSSTQGNGRPGRPSQYRPDGLRSGDGVPPRSLQDGTREGFGHSTSLKVPLARSLQISEELLSRNQLSTAASLGPSGLQNHGQHLILSREASWAKPHYEFNLSRMKFRGNGALSNISDLPFLAENSAFPKMALQAKQDGKKDVSHSSPVDLKIPQVRGMDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQSRKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQPRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKERLGTLKNPPKKKMKLMSG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
70.5
Interspecies Antigen Sequence
Mouse (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LCOR
Entrez GeneID
84458GeneBank Accession#
BC053359.1Protein Accession#
AAH53359.1Gene Name
LCOR
Gene Alias
FLJ38026, KIAA1795, MLR2, RP11-175O19.1
Gene Description
ligand dependent nuclear receptor corepressor
Omim ID
607698Gene Ontology
HyperlinkGene Summary
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM
Other Designations
OTTHUMP00000020179|OTTHUMP00000020180|OTTHUMP00000020181|ligand-dependent corepressor
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Interactome
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Disease
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