LCOR rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LCOR peptide using ARM Technology.
Immunogen
A synthetic peptide of human LCOR is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LCOR peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LCOR
Entrez GeneID
84458GeneBank Accession#
LCORGene Name
LCOR
Gene Alias
FLJ38026, KIAA1795, MLR2, RP11-175O19.1
Gene Description
ligand dependent nuclear receptor corepressor
Omim ID
607698Gene Ontology
HyperlinkGene Summary
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM
Other Designations
OTTHUMP00000020179|OTTHUMP00000020180|OTTHUMP00000020181|ligand-dependent corepressor
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