SYVN1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
SYVN1 transfected lysate.
Western Blot
Lane 1: SYVN1 transfected lysate ( 67.70 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SYVN1 full-length
Host
Human
Theoretical MW (kDa)
67.7
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SYVN1 antibody (H00084447-D01P) by Western Blots.
SDS-PAGE Gel
SYVN1 transfected lysate.
Western Blot
Lane 1: SYVN1 transfected lysate ( 67.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SYVN1
Entrez GeneID
84447GeneBank Accession#
NM_172230.2Protein Accession#
NP_757385.1Gene Name
SYVN1
Gene Alias
HRD1, KIAA1810, MGC40372
Gene Description
synovial apoptosis inhibitor 1, synoviolin
Omim ID
608046Gene Ontology
HyperlinkGene Summary
This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq
Other Designations
synoviolin 1
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Interactome
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Pathway
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