SYVN1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SYVN1 partial ORF ( NP_079434, 238 a.a. - 318 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
HTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.65
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SYVN1
Entrez GeneID
84447GeneBank Accession#
NM_032431Protein Accession#
NP_079434Gene Name
SYVN1
Gene Alias
HRD1, KIAA1810, MGC40372
Gene Description
synovial apoptosis inhibitor 1, synoviolin
Omim ID
608046Gene Ontology
HyperlinkGene Summary
This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq
Other Designations
synoviolin 1
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Interactome
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Pathway
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