AKT1S1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human AKT1S1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human AKT1S1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human AKT1S1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — AKT1S1
Entrez GeneID
84335GeneBank Accession#
AKT1S1Gene Name
AKT1S1
Gene Alias
Lobe, MGC2865, PRAS40
Gene Description
AKT1 substrate 1 (proline-rich)
Omim ID
610221Gene Ontology
HyperlinkGene Summary
AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM
Other Designations
OTTHUMP00000196757|OTTHUMP00000196758|OTTHUMP00000196759|OTTHUMP00000196760|proline-rich Akt substrate, 40 kDa
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Interactome
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