ING5 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ING5 partial ORF ( NP_115705, 24 a.a. - 84 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.45
Interspecies Antigen Sequence
Mouse (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ING5
Entrez GeneID
84289GeneBank Accession#
NM_032329Protein Accession#
NP_115705Gene Name
ING5
Gene Alias
FLJ23842, p28ING5
Gene Description
inhibitor of growth family, member 5
Omim ID
608525Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq
Other Designations
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Interactome
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Disease
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